| Week 1 (4/8/2021) | Cappy's Ope! Wrong Hole vs Playmaker's Blown Run Outs |
| Week 1 (4/8/2021) | WC's South Crazy Cues vs CJ's Orville Barnes |
| Week 1 (4/8/2021) | Steve O's Party Crashers vs Risky's REX |
| Week 2 (4/15/2021) | Playmaker's Blown Run Outs vs Steve O's Party Crashers |
| Week 2 (4/15/2021) | Risky's REX vs WC's South Crazy Cues |
| Week 2 (4/15/2021) | CJ's Orville Barnes vs Cappy's Ope! Wrong Hole |
| Week of 4/22/2021 | No Leagues - Midwest Pool Tournament - No Leagues |
| Week 3 (4/29/2021) | WC's South Crazy Cues vs Playmaker's Blown Run Outs |
| Week 3 (4/29/2021) | CJ's Orville Barnes vs Risky's REX |
| Week 3 (4/29/2021) | Steve O's Party Crashers vs Cappy's Ope! Wrong Hole |
| Week 4 (5/6/2021) | Playmaker's Blown Run Outs vs CJ's Orville Barnes |
| Week 4 (5/6/2021) | Cappy's Ope! Wrong Hole vs Risky's REX |
| Week 4 (5/6/2021) | Steve O's Party Crashers vs WC's South Crazy Cues |
| Week 5 (5/13/2021) | Risky's REX vs Playmaker's Blown Run Outs |
| Week 5 (5/13/2021) | WC's South Crazy Cues vs Cappy's Ope! Wrong Hole |
| Week 5 (5/13/2021) | CJ's Orville Barnes vs Steve O's Party Crashers |
| Week 6 (5/20/2021) | Playmaker's Blown Run Outs vs Cappy's Ope! Wrong Hole |
| Week 6 (5/20/2021) | Risky's REX vs Steve O's Party Crashers |
| Week 6 (5/20/2021) | CJ's Orville Barnes vs WC's South Crazy Cues |
| Week 7 (5/27/2021) | Cappy's Ope! Wrong Hole vs CJ's Orville Barnes |
| Week 7 (5/27/2021) | WC's South Crazy Cues vs Risky's REX |
| Week 7 (5/27/2021) | Steve O's Party Crashers vs Playmaker's Blown Run Outs |
| Week 8 (6/3/2021) | Playmaker's Blown Run Outs vs WC's South Crazy Cues |
| Week 8 (6/3/2021) | Cappy's Ope! Wrong Hole vs Steve O's Party Crashers |
| Week 8 (6/3/2021) | Risky's REX vs CJ's Orville Barnes |
| Week 9 (6/10/2021) | Risky's REX vs Cappy's Ope! Wrong Hole |
| Week 9 (6/10/2021) | WC's South Crazy Cues vs Steve O's Party Crashers |
| Week 9 (6/10/2021) | CJ's Orville Barnes vs Playmaker's Blown Run Outs |
| Week 10 (6/17/2021) | Playmaker's Blown Run Outs vs Risky's REX |
| Week 10 (6/17/2021) | Cappy's Ope! Wrong Hole vs WC's South Crazy Cues |
| Week 10 (6/17/2021) | Steve O's Party Crashers vs CJ's Orville Barnes |
| Week 11 (6/24/2021) | Cappy's Ope! Wrong Hole vs Playmaker's Blown Run Outs |
| Week 11 (6/24/2021) | WC's South Crazy Cues vs CJ's Orville Barnes |
| Week 11 (6/24/2021) | Steve O's Party Crashers vs Risky's REX |
| Week 12 (7/1/2021) | Playmaker's Blown Run Outs vs Steve O's Party Crashers |
| Week 12 (7/1/2021) | Risky's REX vs WC's South Crazy Cues |
| Week 12 (7/1/2021) | CJ's Orville Barnes vs Cappy's Ope! Wrong Hole |